Ayahuasca is a beverage made from Amazonian plants, with very potent psychoactive and hallucinogenic effects. In the Western world, it is often associated with the consumption of psychedelic drugs, as it causes intense visions, alterations of consciousness, and all kinds of physical reactions, often adverse and dangerous. Its origin, however, has been linked for thousands of years to indigenous Amazonian peoples, who use it as traditional medicine in shamanic rituals, spiritual ceremonies, and processes of purging and healing. For these peoples, ayahuasca is not just a mere substance, but also represents the neuralgic center from which they articulate their entire relationship with life and nature. This ancestral aspect, linked to anthropology and biocultural sustainability, is what the World Ayahuasca Forum aims to reclaim, which, for the first time, is taking place at the Girona Congress Palace Auditorium from September 11th to 13th.