Human papillomavirus (HPV), the most common sexually transmitted infection (STI), now affects one in five men. STI specialists warned on Monday of an increase in diagnoses and associated lesions among men over 45, especially those between 60 and 70, who are predominantly heterosexual. In a press release, the Puigvert Foundation explains that those affected belong to generations that have not been protected by routine HPV vaccination and who, at the same time, have experienced a shift in sexual behavior, with an "exponential increase in casual encounters and relationships after a divorce or the end of a relationship." HPV is no longer exclusively a women's disease. The average prevalence of HPV in middle-aged men in Spain is between 30% and 50%, according to reports from hospitals and specialists. Álvaro Vives, head of the STI Unit at the Puigvert Foundation, explains that "it is increasingly common, after ending a long-term relationship, to have multiple sexual partners, participate in open relationships, use dating apps, or frequent swingers' clubs." The main pathologies associated with HPV are, in women, genital warts and cervical cancer, and in men, anal, penile, and head and neck cancers. The incidence of the latter type of tumor is increasing significantly among men aged 60 and 70, and it is projected that more than one million new cases will be diagnosed worldwide each year by 2030. Vives also points out that HPV transmission is not higher among gay men: "Sexual orientation does not constitute a risk group; sexual practices with numerous partners do," he asserts.